2 forms studied
Does choline help with brain fog?
Not on the evidence we can stand behind. Here is every form that has been studied for it, and what each one showed.
Form by form
Strongest first. Evidence for one salt or ester is not evidence for another, so each is rated on its own trials.
Alpha-GPC (Choline Alfoscerate)Mixed
Trials used 315–630 mg · 2 studies · tested as single acute dose of 315 mg or 630 mg, cognitive tests given 60 minutes later, in healthy resistance-trained men
Citicoline (CDP-Choline)No Benefit
Trials used 250–500 mg · 2 studies · tested as citicoline 250-500 mg/day for 28 days in healthy women 40-60 (attention only); pooled data mostly from elderly patients with diagnosed chronic cerebral disease, not healthy adults with everyday mental fatigue