Botox / Dysport / Xeomin
A purified neurotoxin protein injected in tiny doses into targeted muscles to temporarily reduce muscle activity, smoothing dynamic wrinkles and treating certain medical conditions.
How it works
Blocks the release of acetylcholine at the neuromuscular junction, preventing muscle contraction. Effect is fully reversible as nerve endings regenerate over 3–6 months.
Reported benefits
- Reduces crow's feet, frown lines, and forehead wrinkles
- Treats hyperhidrosis (excessive sweating)
- Relieves chronic migraines (medical use)
- Treats jaw clenching (bruxism) and TMJ pain
- Brow lift without surgery
- Neck band (platysmal band) reduction
Regulatory status
Approved for: Glabellar frown lines, Lateral canthal lines (crow's feet), Forehead lines, Chronic migraine, Cervical dystonia, Blepharospasm, Hyperhidrosis
Authorized by EMA; marketed in EU under Botox, Vistabel (cosmetic), Azzalure, Bocouture. CE-marked devices in some applications.
Approved for: Glabellar lines, Crow's feet, Forehead lines, Chronic migraine, Cervical dystonia, Hyperhidrosis
Botulinum toxin is a prescription-only medicine (POM) in the UK. Requires prescription from a registered practitioner. The Health and Care Act 2022 restricted non-surgical cosmetic procedures to licensed practitioners only.
Approved for: Glabellar frown lines (cosmetic), Crow's feet (cosmetic), Forehead lines (cosmetic), Chronic migraine prophylaxis, Cervical dystonia, Hyperhidrosis, Blepharospasm, Overactive bladder
First cosmetic FDA approval in 2002. Multiple cosmetic approvals through 2017. Migraine approved 2010. Multiple brands approved: Botox (Allergan), Dysport (Galderma), Xeomin (Merz), Jeuveau (Evo).
Practical details
Frequency: Every 3–4 months for cosmetic; every 12 weeks for migraines
Results last: Results appear in 3–7 days; last 3–6 months
Contraindications:
- Pregnancy or breastfeeding
- Neuromuscular disorders (myasthenia gravis, ALS)
- Allergy to botulinum toxin or albumin
- Active infection at injection site
- Blood thinners (increased bruising risk)
Always consult a licensed medical professional before undergoing any treatment. This information is educational only and does not constitute medical advice.