Glucosamine + Chondroitin
The pairing sold in most joint-supplement bottles, and the one the largest independent trial actually tested as a single treatment. Its result belongs to the pair, not to either ingredient alone.
What it’s good for
Glucosamine + Chondroitin for Joint Pain
No Benefit2 studies · 0 supporting · 2 against
How it was tested: Pooling ten trials, neither supplement reached a difference a patient would notice. Industry-funded trials reported larger effects than independent ones, and the gap was statistically significant.
Two cartilage components given together, on the theory that they do more paired than singly.
Dose: 1500 mg
Tested as: glucosamine hydrochloride 1500 mg plus chondroitin sulfate 1200 mg daily — the combination as a single treatment, not either ingredient alone