Strong evidenceamino_acid
Glycine for Poor Sleep Quality
Glycine enhances slow-wave (deep) sleep by lowering core body temperature through peripheral vasodilation. It also modulates NMDA receptors and increases serotonin in sleep-regulating brain regions, improving overall sleep architecture.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceKawai N et al. · Neuropsychopharmacology 2015How much to take
3000 mg
Well-studied dose of 3g before bed. Improves subjective sleep quality and next-day alertness.
When to take it
Best taken: evening