enzyme · for high blood pressure
Nattokinase
An enzyme from fermented soybeans, thought to thin the blood slightly and ease pressure.
Say that in clinical terms
Nattokinase is an enzyme extracted from natto (fermented soybeans) that breaks down fibrin and is thought to reduce blood viscosity and modestly suppress renin activity, which can lower blood pressure.
How strong is the research?
A 3-year independent trial in adults without heart disease found no difference from placebo.
4 papers read, 3 supporting, 1 against.
Tested as: Nattokinase 2,000 FU/day (approx. 100 mg NSK-SD softgel) in the primary RCT — note FU (fibrinolytic units) is not mg; potency varies by manufacturer and is not interchangeable across brands. Pooled meta-analysis trials used doses in a similar range.
Who was studied: Adults aged 20 to 80 with mildly raised blood pressure who were not on medication for it.
How much to take
2000 mg