other · for overactive bladder
Pumpkin Seed Extract
Proposed to settle an overactive bladder muscle, though the mechanism is not well established in people.
Say that in clinical terms
Proposed to reduce bladder smooth-muscle overactivity and support pelvic floor/urethral tone via phytosterol and fatty-acid content, though the mechanism is not well established in humans.
How strong is the research?
2 papers read, 2 supporting.
Tested as: The strongest controlled trial (Shim et al. 2014) tested a proprietary 1 g/day blend of pumpkin seed extract plus soy germ extract (branded Cucuflavone) — not pumpkin seed alone, so pumpkin's individual contribution isn't isolated. A separate open-label pilot (Nishimura 2014) tested pumpkin seed oil alone at 10 g/day.
Who was studied: Studied in women aged 35 to 70 with bladder problems.
How much to take
1000 mg