Moderate evidencevitamin
Vitamin B12 for Poor Memory
Vitamin B12 deficiency causes elevated homocysteine which is neurotoxic and associated with hippocampal atrophy. Adequate B12 supports myelin integrity and SAMe-dependent methylation necessary for memory consolidation.
How strong is the research?
Moderate evidence
Based on cohort study data — strong observational evidence.
How much to take
1000–2000 mcg
Particularly important for adults over 50, vegetarians, and those on metformin or PPIs.
When to take it
Best taken: morning