guide · one word, four kinds

Peptides

The collagen in your cupboard is a peptide. So is your wrinkle cream, so is Ozempic, and so is the vial someone is selling on Instagram. One word, very different purchases — here is which is which, and what the research says about each.

What a peptide actually is

A peptide is just a short chain of amino acids — the same building blocks proteins are made of, only fewer of them. That is the entire definition, which is why the word ends up on such wildly different products.

So “is it a peptide?” turns out to be the wrong question. The useful one is which kind you are holding, because a tub of collagen and a vial bought online have almost nothing in common beyond the chemistry class they belong to.

6in a drink
3on your skin
20injected
5prescription

The ones you scoop into a drink

Collagen, whey, and a few others — proteins broken into smaller pieces so they absorb more easily. This is what most people mean when they say they take peptides, and some of it has genuinely good evidence behind it.

Collagen Peptideshydrolysed collagen

Sold for skin elasticity, joint comfort, hair and nails.

See our research →Sold as a supplement

Sold for faster absorption and recovery than whole whey.

What it is →Sold as a supplement
LactotripeptidesIPP and VPP

Sold for lowering blood pressure.

What it is →Sold as a supplement
Carnosinebeta-alanyl-L-histidine

Sold for muscle buffering, anti-glycation, ageing.

What it is →Sold as a supplement
Zinc Carnosinepolaprezinc

Sold for stomach lining and gut repair.

Sold as a supplement
Glutathione

Sold for antioxidant, detoxification, skin brightening.

Sold as a supplement

The ones in your skincare

Serums and creams. You will find these on ingredient lists under names that look alarming and are not. The honest open question for most of them is how much gets through the skin at all.

GHK-Cucopper tripeptide-1

Sold for skin firmness, wrinkles, wound healing, hair growth.

What it is →Skincare ingredient

Sold for collagen stimulation, fine lines.

What it is →Skincare ingredient

Sold for expression lines, marketed as a topical alternative to botulinum toxin.

What it is →Skincare ingredient

The ones sold online for injecting

These are the ones your feed is probably showing you — sold for healing injuries, building muscle, or slowing ageing, usually labelled "for research use only". That label is doing legal work, not describing how they are used. Worth reading the note below before you buy any of them.

Sold for tendon, ligament and gut healing.

What it is →Nobody is seeking approval
TB-500thymosin beta-4 fragment, LKKTETQ

Sold for injury recovery, flexibility, inflammation.

What it is →Nobody is seeking approval

Sold for growth hormone release, fat loss, muscle.

What it is →Nobody is seeking approval

Sold for growth hormone release, recovery, body composition.

What it is →FDA flagged safety concerns

Sold for growth hormone release, appetite, muscle.

What it is →FDA flagged safety concerns

Sold for growth hormone release, appetite, muscle.

What it is →FDA flagged safety concerns

Sold for growth hormone and igf-1, muscle, sleep.

What it is →FDA flagged safety concerns

Sold for reproductive hormones, libido.

What it is →FDA flagged safety concerns

Sold for longevity, telomeres, sleep.

What it is →Nobody is seeking approval

Sold for metabolic health, insulin sensitivity, endurance.

What it is →Nobody is seeking approval

Sold for focus, memory, neuroprotection.

What it is →Nobody is seeking approval

Sold for anxiety, stress.

What it is →Nobody is seeking approval

Sold for tanning without sun, libido.

What it is →Nobody is seeking approval

Sold for fat loss without the growth hormone effects.

What it is →Nobody is seeking approval

Sold for gut inflammation, skin conditions.

What it is →Nobody is seeking approval

Sold for cognition, synapse formation.

What it is →Nobody is seeking approval
PEG-MGFpegylated mechano growth factor

Sold for muscle repair and growth.

What it is →Nobody is seeking approval
LL-37cathelicidin

Sold for antimicrobial, chronic infection, biofilm.

What it is →Nobody is seeking approval

Sold for immune function.

What it is →Nobody is seeking approval
DSIPemideltide, delta sleep-inducing peptide

Sold for sleep.

What it is →Nobody is seeking approval

The ones your doctor can prescribe

Ozempic and its relatives are peptides too. They went through full trials and approval, which is exactly what separates them from the group above.

SemaglutideOzempic, Wegovy

Sold for type 2 diabetes and weight loss — prescription only.

Prescription medicine
TirzepatideMounjaro, Zepbound

Sold for type 2 diabetes and weight loss — prescription only.

Prescription medicine
LiraglutideVictoza, Saxenda

Sold for type 2 diabetes and weight loss — prescription only.

Prescription medicine
TeriparatideForteo

Sold for osteoporosis — prescription only.

Prescription medicine
Insulin

Sold for diabetes — prescription only.

Prescription medicine

If you are thinking about the injectable ones

One thing is worth knowing, because sellers describe it the other way round. The FDA keeps a list of substances it has flagged safety concerns about, and a second list of ones where somebody applied to have them allowed in compounded prescriptions and then withdrew the application. BPC-157, TB-500 and most of the others sit on that second list.

You will see that reported as them being cleared. It is closer to the opposite: nobody is asking for approval any more, so nobody is checking. It is not a verdict against them either — it is an absence of one, and that is genuinely different from a product that has been through trials.

If you are considering one of these, that is a conversation to have with a doctor rather than a comment section. They are also banned in competitive sport.

Why most of these have no rating yet

We rate something only after reading the studies behind it one by one. Three of the 34 here have been through that — collagen, zinc carnosine and glutathione — and they are linked above. The rest are on our list.

Listing something is not recommending it, and a blank is not a criticism. We would rather show you the gap than fill it with a guess.

Check a bottle you already own →

FDA statuses read from Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks (FDA, page content current as of 22 April 2026), checked 18 August 2026. Peptide hormones, growth factors and their mimetics are also prohibited in sport at all times under section S2 of the WADA Prohibited List.