Strong evidenceamino_acid
5-HTP for Anxiety
Enhances serotonergic tone in cortical and limbic regions. May modulate GABAergic activity indirectly.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
5-HTP efficacy and safety in generalized anxiety disorder · 2013How much to take
50–200 mg
Evidence mixed; some benefit in panic disorder. Titrate slowly.