Strong evidencemineral
Magnesium for Anxiety
Magnesium regulates the HPA axis stress response and modulates NMDA glutamate receptors, preventing excitotoxicity. The glycine moiety provides additional inhibitory neurotransmitter activity, enhancing anxiolytic effects.
How strong is the research?
Strong evidence
Based on a meta-analysis of multiple studies — the highest level of research evidence.
Research source
SourceKirkland AE et al. · Nutrients 2018How much to take
200–400 mg
Glycinate form provides calming glycine alongside magnesium. Evening dosing supports relaxation. Can be taken with or without food.
When to take it
Best taken: evening