Strong evidencefatty_acid

Omega-3 for Anxiety

EPA reduces neuroinflammation and modulates the endocannabinoid system. Omega-3s also influence serotonin and dopamine receptor density and signaling in the amygdala and prefrontal cortex, regions central to anxiety.

How strong is the research?

Strong evidence

Based on a meta-analysis of multiple studies — the highest level of research evidence.

Research source

SourceSu KP et al. · JAMA Network Open 2018

How much to take

1000–2000 mg

EPA-dominant formulas (at least 60% EPA) appear more effective for anxiety. Consistent use for 8+ weeks needed.

When to take it

Best taken: with food

All uses of Omega-3All supplements for Anxiety

Other supplements researched for Anxiety