Strong evidenceherb
Berberine for Bloating
Berberine has antimicrobial activity against gas-producing bacteria, supports motility through smooth muscle regulation, reduces intestinal inflammation via NF-kB inhibition, and activates AMPK to improve gut metabolic function.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceChen C et al. · Phytotherapy Research 2015How much to take
500–1500 mg
Take 500mg 2-3 times daily with meals. Start with low dose and increase gradually. May interact with some medications.
When to take it
Best taken: with food