Citicoline (CDP-Choline)

2 studies · 2 supporting · 0 against

Supplies raw material your brain uses to build cell membranes and its memory messenger.

Dose: 250–500 mg

Tested as: citicoline (Cognizin) 500 mg/day (2x250mg) for 12 weeks in healthy older adults (50-85y) with age-associated memory impairment; also 250-500 mg/day for 28 days in healthy women 40-60

2 studies · 0 supporting · 1 against

How it was tested: Pooled trials showed some benefit for memory, but not for attention specifically.

Supplies raw material for the brain’s focus messenger — attention is the most plausible target.

Dose: 250–500 mg

Tested as: citicoline 250-500 mg/day for 28 days in healthy women 40-60 (attention only); pooled data mostly from elderly patients with diagnosed chronic cerebral disease, not healthy adults with everyday mental fatigue