Moderate evidencemineral

Copper for Chronic Fatigue

Ceruloplasmin mobilizes iron from storage, enabling hemoglobin synthesis. Cytochrome c oxidase supports mitochondrial ATP production.

How strong is the research?

Moderate evidence

Based on cohort study data — strong observational evidence.

Research source

SourceBent S et al. · Journal of Alternative and Complementary Medicine 2013

How much to take

1–2 mg

Deficiency rare but possible with high zinc intake or malabsorption. Monitor if supplementing long-term.

All uses of CopperAll supplements for Chronic Fatigue

Other supplements researched for Chronic Fatigue