Strong evidenceantioxidant
CoQ10 for Chronic Fatigue
CoQ10 is essential for mitochondrial electron transport chain function, directly participating in ATP synthesis. Ubiquinol also protects mitochondrial membranes from oxidative damage. Fatigue patients often show depleted CoQ10 levels.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
How much to take
100–300 mg
Ubiquinol form is 3-8x better absorbed than ubiquinone. Take with fat-containing meals. Allow 4-8 weeks for energy improvements.
When to take it
Best taken: with food