CoQ10
The reduced, active form of Coenzyme Q10. Essential for mitochondrial ATP production in the electron transport chain. A powerful lipid-soluble antioxidant that declines with age and statin use.
What it’s good for
CoQ10 improves mitochondrial energy production in neurons, reduces oxidative stress, and inhibits CGRP release. Brain energy deficiency and oxidative stress are key pathogenic factors in migraine.
Dose: 100–300 mg
CoQ10 is essential for mitochondrial electron transport chain function, directly participating in ATP synthesis. Ubiquinol also protects mitochondrial membranes from oxidative damage. Fatigue patients often show depleted CoQ10 levels.
Dose: 100–300 mg
CoQ10 supports sustained mitochondrial ATP production throughout the day. It acts as an electron carrier in the mitochondrial respiratory chain, and afternoon energy dips may partly reflect suboptimal mitochondrial bioenergetics.
Dose: 100–200 mg
CoQ10 is essential for aerobic ATP production in the mitochondrial electron transport chain. It also protects against exercise-induced oxidative stress and improves maximal oxygen consumption (VO2 max) and time to exhaustion.
Dose: 100–300 mg
CoQ10 improves endothelial function by reducing oxidative stress and increasing nitric oxide bioavailability. It preserves nitric oxide from superoxide degradation and may directly relax vascular smooth muscle through bioenergetic mechanisms.
Dose: 100–300 mg