Strong evidenceamino_acid
Creatine for Chronic Fatigue
Maintains cellular energy reserves by replenishing ATP stores. May reduce perceived fatigue via improved mitochondrial function.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceRae C et al. · Proceedings of the Royal Society B 2003How much to take
5 g
Benefits may take 4-6 weeks. Most studied for exercise-induced fatigue but shows promise for chronic conditions.