Strong evidenceherb
Curcumin for Joint Pain
Curcumin inhibits NF-kB, COX-2, LOX, and iNOS inflammatory pathways while downregulating TNF-alpha, IL-1beta, and IL-6 in synovial tissue. It is comparable to NSAIDs for OA pain without GI side effects.
How strong is the research?
Strong evidence
Based on a meta-analysis of multiple studies — the highest level of research evidence.
Research source
SourceDaily JW et al. · Journal of Medicinal Food 2016How much to take
500–1000 mg
Use Meriva, Longvida, CurcuWIN, or BCM-95 for 10-30x better absorption. Take with fat. Allow 4-8 weeks for full anti-inflammatory effect.
When to take it
Best taken: with food