Strong evidencefatty_acid
Omega-3 for Joint Pain
EPA and DHA are converted to anti-inflammatory resolvins, protectins, and maresins. They competitively inhibit pro-inflammatory arachidonic acid conversion to prostaglandins and leukotrienes, reducing synovial inflammation and cartilage degradation.
How strong is the research?
Strong evidence
Based on a meta-analysis of multiple studies — the highest level of research evidence.
Research source
SourceGao H et al. · Nutrients 2017How much to take
2000–3000 mg
Higher doses (2-3g combined EPA+DHA) are used for joint inflammation. EPA is the more anti-inflammatory component.
When to take it
Best taken: with food