other · for hot flashes
Red Clover Isoflavones
Plant compounds that weakly mimic oestrogen, meant to offset the drop that triggers flushes.
Say that in clinical terms
Same phytoestrogen mechanism as soy isoflavones - weak binding to estrogen receptors that may partially offset the estrogen decline driving vasomotor instability.
How strong is the research?
Reductions in mean daily hot flash count at 12 weeks were similar across Promensil (5.1), Rimostil (5.4), and placebo (5.0); neither supplement had a clinically important effect on hot flashes.
4 papers read, 4 against.
Tested as: standardized red clover extracts - Promensil (82 mg/day total isoflavones) and Rimostil (57 mg/day) in the largest trial; an earlier, smaller trial used Promensil 80 mg/day.
Who was studied: Studied in women aged 45 to 60 having at least five hot flushes a day.
How much to take
40–82 mg