No Benefit evidenceother

Soy Isoflavones for Hot Flashes

Isoflavones are plant compounds that weakly bind estrogen receptors, partially compensating for the estrogen decline that destabilizes the brain's temperature-control center; genistein binds estrogen-receptor-beta more selectively than other soy isoflavones.

How strong is the research?

No Benefit evidence

Soy foods and soy extracts are classified as 'not recommended' for vasomotor symptoms (Level I evidence).

How much to take

30–100 mg

All uses of Soy IsoflavonesAll supplements for Hot Flashes

Other supplements researched for Hot Flashes