Strong evidencevitamin
Biotin for Brittle Nails
Biotin enhances nail plate thickness by stimulating keratinocyte growth and improving the cross-linking of keratin proteins in the nail matrix. Clinical trials show 25% increase in nail thickness with supplementation.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceHochman LG et al. · Cutis 1993How much to take
2500–5000 mcg
Biotin is the most studied supplement for nail brittleness. Allow 6-9 months for full nail plate replacement.
When to take it
Best taken: morning