Mixed evidenceenzyme
Bromelain for Joint Pain
Proposed proteolytic and anti-inflammatory action reducing bradykinin and inflammatory mediator activity at the joint.
How strong is the research?
Mixed evidence
12 weeks of bromelain 800 mg/day was not efficacious as an adjunctive treatment of moderate-to-severe knee osteoarthritis versus placebo (no significant difference on primary outcome).
How much to take
500–800 mg