Strong evidenceherb
Lions Mane for Anxiety
NGF-mediated amygdala regulation reduces anxious behavior and stress response reactivity.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceNagano M et al. · Biomed Res 2010How much to take
1000–2000 mg
Anxiolytic effects appear within 4 weeks. Well-tolerated long-term.