Strong evidencemineral
Magnesium Glycinate for Stress
Magnesium regulates the HPA axis by modulating ACTH-driven cortisol release. It also blocks excessive calcium influx through NMDA receptors, preventing stress-induced glutamate excitotoxicity and supporting GABAergic calming pathways.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceBoyle NB et al. · Nutrients 2017How much to take
300–400 mg
Stress depletes magnesium, and magnesium deficiency worsens stress response. Glycinate form adds calming glycine.
When to take it
Best taken: evening