Magnesium
Magnesium chelated with glycine for superior absorption and minimal GI side effects. Supports muscle relaxation, sleep quality, stress response, and over 300 enzymatic reactions in the body.
What it’s good for
Magnesium deficiency is found in up to 50% of migraine sufferers. Magnesium blocks cortical spreading depression, regulates NMDA glutamate receptors, inhibits excessive platelet aggregation, and stabilizes serotonin receptor signaling.
Dose: 400–600 mg
Magnesium regulates the HPA axis stress response and modulates NMDA glutamate receptors, preventing excitotoxicity. The glycine moiety provides additional inhibitory neurotransmitter activity, enhancing anxiolytic effects.
Dose: 200–400 mg
Magnesium modulates NMDA receptors, preventing glutamate excitotoxicity that contributes to irritability. It also regulates the HPA stress axis and supports GABA receptor function, promoting emotional stability.
Dose: 300–400 mg
Magnesium regulates the HPA axis by modulating ACTH-driven cortisol release. It also blocks excessive calcium influx through NMDA receptors, preventing stress-induced glutamate excitotoxicity and supporting GABAergic calming pathways.
Dose: 300–400 mg
Magnesium activates the parasympathetic nervous system, enhances GABA-A receptor binding, and regulates melatonin production via N-acetyltransferase. The glycine moiety activates NMDA receptors in the suprachiasmatic nucleus, lowering core body temperature.
Dose: 300–400 mg
Magnesium enhances sleep quality by increasing slow-wave sleep duration, regulating the circadian clock via melatonin synthesis, and reducing nocturnal cortisol. It modulates GABA receptors promoting deeper, more restorative sleep stages.
Dose: 300–400 mg
Magnesium is essential for muscle relaxation, acting as a natural calcium channel blocker. It regulates the neuromuscular junction by modulating acetylcholine release and supporting the calcium-magnesium ATPase pump that returns muscles to resting state.
Dose: 300–400 mg
Magnesium reduces paraspinal muscle spasm by acting as a natural calcium channel blocker and supporting GABA-mediated inhibitory signaling. It also has anti-inflammatory and analgesic properties through NMDA receptor modulation.
Dose: 300–400 mg
Magnesium acts as a natural calcium channel blocker, relaxing vascular smooth muscle and reducing peripheral vascular resistance. It also improves endothelial function, increases nitric oxide production, and reduces angiotensin II effects.
Dose: 300–500 mg
Magnesium relaxes intestinal smooth muscle, supports peristaltic contractions, draws water into the intestinal lumen for softer stools, and is a cofactor for digestive enzymes. Glycinate form provides gentle, non-osmotic bowel support.
Dose: 200–400 mg
Magnesium acts as a mild antacid, neutralizing excess gastric acid. It also supports lower esophageal sphincter tone through smooth muscle regulation and reduces stress-related acid hypersecretion via HPA axis modulation.
Dose: 200–400 mg