Moderate evidencemineral
Manganese for Joint Pain
Essential cofactor for glycosyltransferases in cartilage proteoglycan synthesis. MnSOD scavenges superoxide in chondrocytes.
How strong is the research?
Moderate evidence
Based on cohort study data — strong observational evidence.
How much to take
2–5 mg
Upper limit 11 mg/day. Glycinate form preferred for absorption. Take with meals.