No Benefit evidenceherb
Saw Palmetto for Prostate Symptoms
Proposed to inhibit 5-alpha-reductase and reduce inflammatory/growth signaling in prostate tissue, lowering intraprostatic DHT; this has not translated into a measurable symptom benefit in rigorous trials.
How strong is the research?
No Benefit evidence
Dose escalation to 320, then 640, then 960 mg/day over 72 weeks produced no benefit over placebo on AUA symptom score or any secondary measure (flow rate, prostate volume, PSA, nocturia, quality of life). This is the CAMUS trial.
How much to take
320–960 mg
When to take it
Best taken: with food