Strong evidenceherb
Ashwagandha for Irritability
Ashwagandha reduces cortisol by up to 30% and modulates GABAergic signaling, both of which help stabilize mood and reduce stress-induced irritability. It also supports serotonin receptor balance.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
How much to take
300–600 mg
Adaptogenic effects help buffer stress-related irritability. Allow 4-6 weeks for stabilization of mood.
When to take it
Best taken: evening