other
MSM
A sulfur compound added to most joint formulas. The trials behind it are small, short, and mostly funded by its suppliers.
What it’s good for
2 studies · 1 supporting · 1 against
A sulfur compound, proposed to lower inflammatory signalling.
Dose: 3000–6000 mg
Tested as: MSM alone — but measured as a side finding in trials designed to look at something else
2 studies · 1 supporting · 1 against
Proposed to reduce the oxidative stress that follows hard exercise.
Dose: 3000 mg
Tested as: MSM alone, around 3 g daily, in very small groups of exercising adults
MSM for Joint Pain
No Benefit4 studies · 2 supporting · 1 against
How it was tested: The largest trial of MSM on its own found no benefit.
A sulfur compound, meant to lower inflammation and oxidative stress in the joint.
Dose: 3000–6000 mg
Tested as: MSM alone, 3–6 g daily for up to twelve weeks