inflammation · symptom

Chronic Inflammation

Your immune system running hot in the background.

30 supplements reviewed6 proven

Top proven supplements

Studied in people, at a dose you can actually buy.6

Studied in people, at a dose you can actually buy.

Omega-32000–3000 mg · with_food

Your body turns EPA and DHA into the signals that actively shut inflammation down.

Solid · 1 study, positiveResearch →
Quercetin500–1000 mg · any

Steadies the immune cells that release histamine and other inflammatory chemicals.

Strong · 1 study, positiveResearch →
Curcumin500–1000 mg · with_food

Turns down the master switch your body uses to start inflammation.

Strong · 4 of 4 studies agreeResearch →
Garlic600–1200 mg · any

Turns down the pathway that drives inflammatory signals in the blood.

Solid · 2 of 2 studies agreeResearch →
Resveratrol150–500 mg · any

Switches on your cells’ repair pathways and quietens inflammatory signalling.

Solid · 2 of 2 studies agreeResearch →

Might help

Real research, but thin or split. Worth knowing, not worth counting on.12

Real research, but thin or split. Worth knowing, not worth counting on.

Glutathione250–500 mg · any

Your body’s main antioxidant, which mops up the damage that drives inflammation.

Evidence · 1 study, positiveResearch →
N-Acetyl Cysteine600–1800 mg · any

Raw material for your body’s main antioxidant, which quietens inflammatory signalling.

Evidence · 1 study, positiveResearch →
Vitamin C500–2000 mg · any

Your immune system needs vitamin C. The theory is that topping up a low level calms inflammation.

Mixed · 1 of 2 studies positiveResearch →
Bromelain200–1050 mg · any

A pineapple enzyme, proposed to lower the inflammatory markers circulating in your blood.

Evidence · 1 study, positiveResearch →
Melatonin3–10 mg · any

It is an antioxidant and influences immune signalling, which is the basis for the claim.

Evidence · 2 of 2 studies agreeResearch →
Cocoa Flavanols500 mg · any

Proposed to lower the low-grade inflammation of ageing, through effects on blood vessels.

Mixed · 1 of 2 studies positiveResearch →
MSM3000–6000 mg · any

A sulfur compound, proposed to lower inflammatory signalling.

Mixed · 1 of 2 studies positiveResearch →
Chondroitin600 mg · any

Proposed to quieten the inflammation around a worn joint.

Evidence · 1 study, positiveResearch →
Lycopene7–50 mg · any

A strong antioxidant. Less oxidative stress is thought to mean less inflammatory signalling.

Mixed · 3 of 4 studies positiveResearch →
Black Seed Oil500–2000 mg · any

Its active compound blocks the switch that turns inflammatory genes on.

Mixed · 3 of 4 studies positiveResearch →
Vitamin D2000–4000 IU · morning

Steers your immune system away from its inflammatory setting and toward its calming one.

Mixed · 2 of 3 studies positiveResearch →

Tested — didn’t work

Measured properly against placebo. Nothing found.5

Measured properly against placebo. Nothing found.

EGCG400–800 mg · any

Its catechins are meant to block the pathways that drive inflammatory signalling.

No benefit foundResearch →
Collagen3–15 g · any

There is no established route by which swallowed collagen would lower inflammation in the body.

No benefit foundResearch →
Psyllium7–14 g · any

The idea was that lowering cholesterol and blood sugar would calm inflammation as a knock-on.

No benefit foundResearch →
Vitamin K1500–1000 mcg · any

Meant to turn down the switch that makes inflammatory signals.

No benefit foundResearch →

No research yet

People take these for it. We haven’t found trials we would stand behind.7

People take these for it. We haven’t found trials we would stand behind.

Selenium100–200 mcg · with_food

Selenium-based enzymes mop up the oxidative damage that drives inflammation.

No trials we can vouch forResearch →
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