Strong evidencefatty_acid
Omega-3 for Acne
Omega-3 fatty acids (especially EPA) inhibit leukotriene B4 and prostaglandin E2 production, both key mediators of acne inflammation. They also modulate IGF-1 signaling and reduce sebocyte lipogenesis driven by the Western diet.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceKhayef G et al. · Lipids in Health and Disease 2012How much to take
1000–2000 mg
EPA has stronger anti-inflammatory effects relevant to acne. Take with food consistently.
When to take it
Best taken: with food