Strong evidencevitamin
Vitamin A for Acne
Vitamin A normalizes keratinocyte differentiation preventing follicular hyperkeratinization (comedones). It reduces sebaceous gland activity, modulates inflammatory gene expression, and supports skin cell turnover to prevent pore clogging.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceLayton A · Dermatologic Clinics 2009How much to take
5000–10000 IU
Moderate doses for acne support. Higher therapeutic doses (up to 300,000 IU) should only be used under medical supervision. Do not use during pregnancy.
When to take it
Best taken: with food