Strong evidencevitamin
Vitamin K2 for Joint Pain
Activates matrix Gla protein (MGP) which inhibits calcium deposition in cartilage and soft tissues, reducing joint calcification.
How strong is the research?
Strong evidence
Based on a randomised controlled trial (RCT) — the gold standard for establishing cause and effect.
Research source
SourceNeogi T et al. · Arthritis & Rheumatology 2019How much to take
90–180 mcg
Take with fat-containing meal for absorption. MK-7 has longer half-life than MK-4.
When to take it
Best taken: with food