Mixed evidenceantioxidant
Cocoa Flavanols for Chronic Inflammation
Proposed to reduce chronic low-grade inflammation ('inflammaging') via nitric-oxide-mediated endothelial effects and antioxidant activity.
How strong is the research?
Mixed evidence
Across 33 RCTs (9 acute, 24 regular consumption), most inflammatory biomarkers were unchanged with regular cocoa intake in healthy people; more consistent anti-inflammatory responses were seen in people with type 2 diabetes. Review noted 40% of included trials had industry funding and 82% received free cocoa products from industry.
How much to take
500 mg